Weak/Considerable Metabolizers, CYP2D6 The development in the active metabolite, M1, is mediated by CYP2D6, a polymorphic enzyme. Somewhere around seven% on the population has lessened action in the CYP2D6 isoenzyme of cytochrome P450 metabolizing enzyme system. These individuals are “very poor metabolizers” of debrisoquine, dextromethorphan and tricyclic antidepressants, amongst other https://larryq642ouz7.luwebs.com/profile