This mechanism might be through the induction of hepatic microsomal enzymes that metabolize the antibiotic. If phenobarbital and doxycycline are administered concurrently, the clinical reaction to doxycycline need to be monitored carefully. Phenytoin, sodium valproate, valproic acid: The influence of barbiturates around the metabolism of phenytoin appears to get variable. https://pain-killers56890.blog5.net/69352447/lsds-no-further-a-mystery