Disruption of HER2–HER3 dimerization is vital for HER2-driven signalling and is also focused effectively by pertuzumab132. The positive benefits from pertuzumab trials supported a method of focusing on HER3, that has an important function in HER2-mediated tumorigenesis. HER3 is unique when compared with other HER family members as it truly https://www.directivepublications.org/journal-of-clinical-breast-cancer/